Nikki Moody scored 14 points and had 10 assists to lead No. 14 Iowa State over Holy Cross 72-50 on Saturday.
The Cyclones (10-0) shot 47 percent from the floor, including 11 of 32 (34 percent) from beyond the arc. Jadda Buckley added 12 points, while Hallie Christofferson and Nicole Blaskowski both chipped in with 11 points.
Holy Cross (7-3) was led by Raquel Scott's 14 points and Molly Hourigan added 10 points.
The Crusaders scored the first six points of the game, but Iowa State quickly took over. Tied at 10, the Cyclones outscored Holy Cross 31-12 the rest of the half to take a 19-point lead at 41-22 into the break.
Iowa State used a 15-0 run at the start of the second half, pushing the lead to 60-25, to ensure the blowout. Holy Cross managed an 11-2 run in the final 4:23 to make the final more respectable.