Jake Rudock and Mark Weisman each ran for a pair of touchdowns and Iowa beat Missouri State 28-14 on Saturday, snapping a seven-game losing streak dating back to 2012.
Weisman had 180 yards rushing for the Hawkeyes (1-1), who prevailed despite a somewhat shaky performance against an FCS opponent.
Weisman scored on runs of 10 and 3 yards to help the Hawkeyes take a 21-0 lead late in the third quarter.
Missouri State answered with touchdowns on back-to-back plays from scrimmage early in the fourth quarter, pulling within 21-14 with 14:15 to go.
Rudock's 2-yard TD run put Iowa back ahead 28-14, and Tanner Miller sealed it with an interception in the end zone with 6:50 left.
Kierra Harris threw for 127 yards and a TD for Missouri State (0-2).