Jordan Clarkson scored 21 points, including all 11 free throw attempts, as Missouri held off Vanderbilt 67-64 on Wednesday.
Earnest Ross added 16 points for the Tigers (19-7, 7-6 SEC), who survived an off-game from top scorer Jabari Brown in a matchup of schools tied for fifth place in the conference.
Brown, held to nine points on 3 for 11 shooting, averaged 23.9 points the previous 10 games including 22 the first meeting at Vanderbilt last month.
Damian Jones had 19 points and seven rebounds for Vanderbilt (14-11, 6-7).
Down eight points with just over two minutes to go, the Commodores shaved the deficit to two on Kyle Moats' 3-pointer with 19.4 seconds to go.
Kyle Fuller's bid to force overtime on a shot that drew iron from beyond midcourt came after the buzzer.
Fuller made just one of 12 shots and had four points, eight below his average.